Articular manifestations associated with parvo B19 infection
The articular manifestations of parvo B19 are more common in adults than in children and in women than in men.
The reported frequency of arthritis due to parvo B19 in adults is as high as 50% to 80%. Symptoms initially begin in a few joints and rapidly involve more joints in an additive fashion.
In adults, the pattern is more RA-like, symmetrically affecting the wrists, metacarpophalangeal, and PIP joints. In children, the pattern is usually asymmetric and oligoarticular involving the large joints (e.g., knees).
