Acromegaly

What is Acromegaly

Acromegaly is a hormone disorder that causes unusual growth of the body in adults. It commonly affects the bones of the hands, feet, and face. Over time, acromegaly can lead to a number of problems or other conditions, such as:

  • Diabetes mellitus.
  • Thyroid problems.
  • Colon polyps.
  • Osteoarthritis.
  • Heart disease.
  • Sleep apnea.
  • High blood pressure (hypertension).

What are the causes?

This condition can be caused when the body produces more growth hormone than it needs. This can result from:

  • A non-cancerous (benign) tumor on the gland that produces growth hormone (pituitary gland). This is a common cause.
  • A tumor in another part of the body, such as the adrenal gland or lungs. This is a rare cause.

What are the signs or symptoms?

Common signs and symptoms of this condition include:

  • Larger-than-normal hands, feet, head, face, brow, or jaw.
  • Swelling of the hands or feet.
  • Headaches.
  • Fatigue or weakness.
  • Enlarged heart, liver, kidneys, spleen, or other internal organs.
  • Severe problems with snoring or sleep apnea.
  • Blurred vision.
  • Joint pain.
  • Skin changes, such as skin tags or coarse skin.
  • Widely spaced teeth.
  • Numbness or tingling in the fingers.
  • Menstrual cycle changes in women.
  • Erectile dysfunction in men.

How is this diagnosed?

This condition may be diagnosed based on:

  • A physical exam.
  • Blood tests.
  • Imaging tests, such as an MRI or a CT scan.

How is this treated?

This condition may be treated with:

  • Surgery to remove the tumor that is causing the condition.
  • Medicines. Medicines may be given instead of surgery, or they may be given before surgery to shrink the tumor. They may also be given after surgery:
    • If the surgery is not successful.
    • If hormone levels do not return to normal.
  • Radiation therapy. This is used if surgery and medicines are not effective.

Follow these instructions at home:

  • Keep all follow-up visits as told by your health care provider. It is important to keep follow-up appointments all through your life so that your health care provider can:
    • Check whether your pituitary gland is working normally.
    • Look for complications of the disease.
  • Get eye exams regularly.
  • Take over-the-counter and prescription medicines only as told by your health care provider.

Contact a health care provider if:

  • You have changes in your vision.
  • Your headaches get worse.
  • You have new symptoms or new pain or numbness.
  • Your symptoms do not get better with treatment.

Get help right away if:

  • You have pain or pressure in your chest.
  • You have difficulty breathing.
  • You pass out or feel faint.

Summary

  • Acromegaly is a hormone disorder that causes unusual growth of the body in adults. It commonly affects the bones of the hands, feet, and face.
  • Over time, acromegaly can lead to a number of problems or other conditions.
  • This condition can be caused when the body produces more growth hormone than it needs.
  • Acromegaly is most commonly caused by a non-cancerous (benign) tumor on the gland that produces growth hormone (pituitary gland).
  • This condition may be treated with surgery to remove a tumor, medicines, or radiation.
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