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What is Ulipristal
Ulipristal is a progesterone agonist/antagonist emergency contraceptive. It is indicated to prevent pregnancy after unprotected intercourse or a known or suspected contraceptive failure for up to 5 days after intercourse and is available only by prescription in the U.S.
Brand Name
Ella
Indications
- postcoital contraception
- uterine leiomyomata
Monitoring Parameters
- pregnancy testing
Contraindications
- acquired immunodeficiency syndrome (AIDS)
- breast-feeding
- children
- contraception requirements
- ectopic pregnancy
- hepatic disease
- human immunodeficiency virus (HIV) infection
- menstrual irregularity
- pregnancy
- sexually transmitted disease
Drug Interactions
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Aldesleukin, IL-2
- Amiodarone
- Amobarbital
- Amoxicillin; Clarithromycin; Lansoprazole
- Amoxicillin; Clarithromycin; Omeprazole
- Amprenavir
- Apalutamide
- Armodafinil
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Atazanavir
- Atazanavir; Cobicistat
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Barbiturates
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Bexarotene
- Boceprevir
- Bosentan
- Butabarbital
- Carbamazepine
- Cenobamate
- Ceritinib
- Chloramphenicol
- Cimetidine
- Clarithromycin
- Clobazam
- Cobicistat
- Cobimetinib
- Colchicine
- Colchicine; Probenecid
- Conivaptan
- Cyclosporine
- Dabigatran
- Dabrafenib
- Danazol
- Darunavir
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Deferasirox
- Delavirdine
- Dexamethasone
- Dextromethorphan; Quinidine
- Digoxin
- Diltiazem
- Dronedarone
- Edoxaban
- Efavirenz
- Efavirenz; Emtricitabine; Tenofovir
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Enzalutamide
- Erythromycin
- Erythromycin; Sulfisoxazole
- Eslicarbazepine
- Etravirine
- Felbamate
- Fexofenadine
- Fexofenadine; Pseudoephedrine
- Fluconazole
- Fluoxetine
- Fluoxetine; Olanzapine
- Flutamide
- Fluvoxamine
- Fosamprenavir
- Fosphenytoin
- grapefruit juice
- Griseofulvin
- Idelalisib
- Imatinib
- Indinavir
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Isoniazid, INH; Rifampin
- Itraconazole
- Ivosidenib
- Ketoconazole
- Lesinurad
- Lesinurad; Allopurinol
- Letermovir
- Loperamide
- Loperamide; Simethicone
- Lopinavir; Ritonavir
- Lorlatinib
- Lumacaftor; Ivacaftor
- Lumacaftor; Ivacaftor
- Mefloquine
- Mephobarbital
- Methohexital
- Mitotane
- Modafinil
- Nefazodone
- Nelfinavir
- Nevirapine
- Nicardipine
- Octreotide
- Ombitasvir; Paritaprevir; Ritonavir
- Omeprazole; Amoxicillin; Rifabutin
- Oxcarbazepine
- Pentobarbital
- Phenobarbital
- Phentermine; Topiramate
- Phenytoin
- Posaconazole
- Primidone
- Progestins
- Quinidine
- Quinine
- Ranolazine
- Ribociclib
- Ribociclib; Letrozole
- Rifabutin
- Rifampin
- Rifapentine
- Ritonavir
- Rivaroxaban
- Saquinavir
- Secobarbital
- St. John’s Wort, Hypericum perforatum
- Telithromycin
- Telotristat Ethyl
- Thiopental
- Tipranavir
- Topiramate
- Topotecan
- Trandolapril; Verapamil
- Tucatinib
- Verapamil
- Voriconazole
- Zafirlukast
Side Effects
- abdominal pain
- acne vulgaris
- breakthrough bleeding
- dizziness
- dysmenorrhea
- fatigue
- headache
- menstrual irregularity
- nausea
