Oxymetholone Brand Name– Anadrol
What is Oxymetholone
Oxymetholone is an oral anabolic steroid. Oxymetholone (ANADROL-50) is used for the treatment of anemias including acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and hypoplastic anemias associated with myelotoxic drug administration.
Oxymetholone has also been studied for the treatment of HIV-wasting.
Oxymetholone was FDA approved in January 1972. The use of anabolic steroids, such as oxymetholone, are prohibited in competing athletes by the US and International Olympic Committees and other athletic organizations.
Indications
- AIDS-associated wasting syndrome
- anemia
- aplastic anemia
- hypoplastic anemia
- myelofibrosis
For the treatment of anemia caused by deficient red cell production, including aplastic anemia (acquired and congenital), myelofibrosis, and hypoplastic anemia due to myelotoxic drugs
Side Effects
- acne vulgaris
- alopecia
- anemia
- bladder discomfort
- chills
- clitoromegaly
- decreased ejaculate volume
- diarrhea
- dysphonia
- edema
- elevated hepatic enzymes
- epididymitis
- excitability
- gynecomastia
- hepatic necrosis
- hirsutism
- hypercalcemia
- hyperchloremia
- hyperkalemia
- hyperlipidemia
- hyperphosphatemia
- impotence (erectile dysfunction)
- infertility
- insomnia
- jaundice
- libido decrease
- libido increase
- menstrual irregularity
- muscle cramps
- nausea
- new primary malignancy
- oligospermia
- peliosis hepatis
- penile enlargement
- polycythemia
- priapism
- sodium retention
- testicular atrophy
- tumorigenicity
- vomiting
Monitoring Parameters
- growth rate
- hemoglobin/hematocrit
- LFTs
- serum calcium
- serum iron
- serum lipid profile
Contraindications
- breast cancer
- breast-feeding
- children
- diabetes mellitus
- females
- geriatric
- hepatic disease
- hypercholesterolemia
- hyperlipidemia
- infants
- neonates
- new primary malignancy
- peliosis hepatis
- pregnancy
- prostate cancer
- renal disease
- tumorigenicity
Interactions
- Abarelix
- Acarbose
- Alogliptin
- Alogliptin; Metformin
- Alogliptin; Pioglitazone
- Alpha-glucosidase Inhibitors
- Azelastine; Fluticasone
- Beclomethasone
- Betamethasone
- Budesonide
- Budesonide; Formoterol
- Canagliflozin
- Canagliflozin; Metformin
- Ciclesonide
- Corticosteroids
- Cortisone
- Cyclosporine
- Dapagliflozin
- Dapagliflozin; Metformin
- Dapagliflozin; Saxagliptin
- Darbepoetin Alfa
- Deflazacort
- Degarelix
- Dexamethasone
- Dipeptidyl Peptidase-4 Inhibitors
- Empagliflozin
- Empagliflozin; Linagliptin
- Empagliflozin; Linagliptin; Metformin
- Empagliflozin; Metformin
- Epoetin Alfa
- Ertugliflozin
- Ertugliflozin; Metformin
- Ertugliflozin; Sitagliptin
- Fludrocortisone
- Flunisolide
- Fluticasone
- Fluticasone; Salmeterol
- Fluticasone; Umeclidinium; Vilanterol
- Fluticasone; Vilanterol
- Formoterol; Mometasone
- Glipizide; Metformin
- Glyburide; Metformin
- Goserelin
- Histrelin
- Hydrocortisone
- Incretin Mimetics
- Insulins
- Leuprolide
- Leuprolide; Norethindrone
- Linagliptin
- Linagliptin; Metformin
- Meglitinides
- Metformin
- Metformin; Pioglitazone
- Metformin; Repaglinide
- Metformin; Rosiglitazone
- Metformin; Saxagliptin
- Metformin; Sitagliptin
- Methoxy polyethylene glycol-epoetin beta
- Methylprednisolone
- Miglitol
- Mometasone
- Nafarelin
- Pramlintide
- Prednisolone
- Prednisone
- Saw Palmetto, Serenoa repens
- Saxagliptin
- SGLT2 Inhibitors
- Simvastatin; Sitagliptin
- Sitagliptin
- Sulfonylureas
- Thiazolidinediones
- Triamcinolone
- Triptorelin
- Warfarin
