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What is Oxychlorosene
Oxychlorosene is a topical irrigant antiseptic historically used as an adjuvant for treating or preventing localized infections.
Oxychlorosene exerts its antiseptic properties through chlorinization and oxidation but is less toxic and irritating than similar acting agents including Dakin’s solution and sodium hypochlorite (household bleach) because it is slightly acidic rather than alkaline.
Oxychlorosene should not be used to treat systemic infections. According to the manufacturer, oxychlorosene has activity against gram-positive and gram-negative bacteria, fungi, yeast, mold, viruses, and spores.
The irrigation solution is used to remove necrotic debris in massive infections or from radiation necrosis, for antimicrobial prophylaxis and treatment pre- and post-operatively, and for cleansing/disinfecting wounds. It can be applied topically or into body cavities by irrigation, instillation, spray, soaks, or wet compresses. The oxychlorosene solution should only be used when it will be in direct contact with the affected area.
Oxychlorosene has been in use since 1954, but has never been formally approved as a drug by the FDA drug approval process.
This drug has not been found by FDA to be safe and effective, and the product labeling has not been approved by FDA.
Indications
- amebiasis
- bowel preparation
- burn wound infection
- burns
- carbuncle
- cellulitis
- cervicitis
- cystitis
- dacryocystitis
- decubitus ulcer
- dermatitis
- furunculosis
- gas gangrene
- interstitial cystitis
- oropharyngeal candidiasis (thrush)
- osteomyelitis
- pharyngitis
- proctitis
- sinusitis
- skin and skin structure infections
- stomatitis
- surgical infection prophylaxis
- tonsillitis
- urinary tract infection (UTI)
- vaginitis
- wound management
For surgical infection prophylaxis
for surgical infection prophylaxis in general surgery as skin preparation
Side Effects
- bladder discomfort
- ocular pain
- skin irritation
- skin necrosis
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- accidental exposure
- bladder obstruction
- breast-feeding
- pregnancy
- urethral stricture
Interactions
No information is available regarding drug interactions associated with Oxychlorosene
