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Lactulose Brand Names
Acilac | Cephulac | Cholac | Chronulac | Constilac | Constulose | Enulose | Generlac | Kristalose
What is Lactulose
Lactulose a synthetic derivative of lactose, is a disaccharide sugar containing one molecule of galactose and one molecule of fructose. Lactulose is used in the treatment of hepatic encephalopathy and as a laxative.
Clinical response in the treatment of hepatic encephalopathy is about equal to that of neomycin.
Lactulose was approved by the FDA in 1976.
Indications
- constipation
- hepatic encephalopathy
For the treatment of hepatic encephalopathy (portal-systemic encephalopathy, PSE)
Side Effects
- abdominal pain
- diarrhea
- eructation
- flatulence
- hypernatremia
- hypokalemia
- metabolic acidosis
- nausea
- vomiting
Monitoring Parameters
- plasma ammonia concentrations
- serum electrolytes
Contraindications
- breast-feeding
- diabetes mellitus
- galactose-free diet
- geriatric
- pregnancy
- surgery
Interactions
- Acetaminophen; Hydrocodone
- Antacids
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Bisacodyl
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Bumetanide
- Calcium Carbonate
- Calcium Carbonate; Magnesium Hydroxide
- Calcium Carbonate; Risedronate
- Calcium Carbonate; Simethicone
- Calcium Phosphate, Supersaturated
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Castor Oil
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Dichlorphenamide
- Diphenhydramine; Hydrocodone; Phenylephrine
- Ethacrynic Acid
- Furosemide
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Homatropine; Hydrocodone
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Lanthanum Carbonate
- Loop diuretics
- Lubiprostone
- Magnesium Citrate
- Magnesium Salts
- Methylcellulose
- Mineral Oil
- Neomycin
- Omeprazole; Sodium Bicarbonate
- Polycarbophil
- Polyethylene Glycol
- Polyethylene Glycol; Electrolytes
- Polyethylene Glycol; Electrolytes; Ascorbic Acid
- Polyethylene Glycol; Electrolytes; Bisacodyl
- Psyllium
- Senna
- Sodium Bicarbonate
- Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous
- Torsemide
