Iopromide Brand Name– Ultravist
What is Iopromide
Iopromide is an iodinated, nonionic radiographic contrast agent indicated for cerebral and peripheral arteriography; coronary arteriography and left ventriculography, visceral angiography, and aortography; excretory urography; contrast computed tomography (CT) of the head and body.
Iopromide is only approved for intravascular administration; avoid inadvertent intrathecal administration as this can result in serious adverse events, including death. Serious and potentially fatal adverse events (i.e., cardiovascular toxicities, hypersensitivity reactions, severe cutaneous adverse reactions, acute renal failure) may also occur during intravascular use.
To minimize the toxicity risk, ensure the patients are adequately hydrated, and use the smallest necessary volume and concentration of iopromide.
Indications
- angiography
- computed tomography (CT) imaging
- urography
Side Effects
- abdominal pain
- acute generalized exanthematous pustulosis (AGEP)
- acute respiratory distress syndrome (ARDS)
- agitation
- amnesia
- anaphylactic shock
- anaphylactoid reactions
- angina
- angioedema
- anxiety
- aphasia
- apnea
- arachnoiditis
- arthralgia
- asthenia
- atrial fibrillation
- AV block
- back pain
- bradycardia
- bronchospasm
- cardiac arrest
- cerebral edema
- chest pain (unspecified)
- chills
- coma
- confusion
- conjunctivitis
- constipation
- cough
- diabetes insipidus
- diarrhea
- dizziness
- Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
- dysgeusia
- dyspepsia
- dysphagia
- dyspnea
- dysuria
- epistaxis
- erythema
- fever
- flushing
- headache
- heart failure
- hematoma
- hematuria
- hyperesthesia
- hyperhidrosis
- hypertension
- hyperthermia
- hyperthyroidism
- hypertonia
- hypotension
- hypothyroidism
- hypoxia
- injection site reaction
- lacrimation
- laryngeal edema
- laryngospasm
- leukocytosis
- maculopapular rash
- malaise
- migraine
- muscle cramps
- muscle paralysis
- musculoskeletal pain
- myasthenia
- mydriasis
- myocardial infarction
- nasal congestion
- nausea
- nephrotoxicity
- palpitations
- paresis
- paresthesias
- peripheral edema
- peripheral vasodilation
- pharyngitis
- pleural effusion
- polydipsia
- pruritus
- pulmonary edema
- pulmonary hypertension
- rash
- renal failure (unspecified)
- respiratory arrest
- rhabdomyolysis
- seizures
- sinus tachycardia
- skin necrosis
- sneezing
- Stevens-Johnson syndrome
- stroke
- syncope
- tenesmus
- throat irritation
- thrombosis
- thyrotoxicosis
- tinnitus
- toxic epidermal necrolysis
- tremor
- urinary retention
- urinary urgency
- urticaria
- ventricular fibrillation
- vertigo
- visual impairment
- vomiting
- xerostomia
Monitoring Parameters
- serum creatinine/BUN
Contraindications
- asthma
- atopy
- breast-feeding
- cardiac disease
- children
- coagulopathy
- dehydration
- diabetes mellitus
- emphysema
- extravasation
- females
- heart failure
- hepatic disease
- hyperthyroidism
- hypothyroidism
- infants
- intrathecal administration
- iodine hypersensitivity
- multiple myeloma
- myasthenia gravis
- neonates
- pheochromocytoma
- pregnancy
- premature neonates
- pulmonary disease
- pulmonary hypertension
- QT prolongation
- radiation exposure
- radiopaque contrast media hypersensitivity
- renal disease
- renal failure
- renal impairment
- serious rash
- sickle cell disease
- thromboembolic disease
- thyroid disease
- thyrotoxicosis
- valvular heart disease
Interactions
- Acebutolol
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Tramadol
- Acyclovir
- Aldesleukin, IL-2
- Alogliptin; Metformin
- Aminoglycosides
- Amiodarone
- Amitriptyline
- Amitriptyline; Chlordiazepoxide
- Amoxapine
- Amphetamine
- Amphetamine; Dextroamphetamine
- Amphetamine; Dextroamphetamine Salts
- Amphotericin B
- Angiotensin-converting enzyme inhibitors
- Aprotinin
- Aripiprazole
- Asenapine
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Atenolol
- Atenolol; Chlorthalidone
- Bendroflumethiazide; Nadolol
- Benzphetamine
- Beta-blockers
- Betaxolol
- Bictegravir; Emtricitabine; Tenofovir Alafenamide
- Bisoprolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Brexpiprazole
- Brimonidine; Timolol
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Dextromethorphan; Phenylephrine
- Bumetanide
- Bupropion
- Bupropion; Naltrexone
- Caffeine
- Caffeine; Ergotamine
- Canagliflozin; Metformin
- Capreomycin
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Phenylephrine
- Carteolol
- Carvedilol
- Chlophedianol; Guaifenesin; Phenylephrine
- Chlorpheniramine; Dextromethorphan; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Phenylephrine
- Cisplatin
- Clomipramine
- Clozapine
- Cocaine
- Codeine; Phenylephrine; Promethazine
- Colistimethate, Colistin, Polymyxin E
- Cyclobenzaprine
- Cyclosporine
- Dapagliflozin; Metformin
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Deferasirox
- Desipramine
- Dexmethylphenidate
- Dextroamphetamine
- Dextromethorphan; Diphenhydramine; Phenylephrine
- Dextromethorphan; Guaifenesin; Phenylephrine
- Diethylpropion
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Phenylephrine
- Dopamine
- Doravirine; Lamivudine; Tenofovir disoproxil fumarate
- Dorzolamide; Timolol
- Doxepin
- Efavirenz; Emtricitabine; Tenofovir
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Empagliflozin; Linagliptin; Metformin
- Empagliflozin; Metformin
- Emtricitabine; Rilpivirine; Tenofovir alafenamide
- Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
- Emtricitabine; Tenofovir alafenamide
- Emtricitabine; Tenofovir disoproxil fumarate
- Entecavir
- Ephedrine
- Ertugliflozin; Metformin
- Esmolol
- Ethacrynic Acid
- Ethanol
- Fluoxetine; Olanzapine
- Furosemide
- Glipizide; Metformin
- Glyburide; Metformin
- Green Tea
- Guaifenesin; Phenylephrine
- Haloperidol
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrocodone; Phenylephrine
- Ibandronate
- Iloperidone
- Imipramine
- Labetalol
- Lamivudine; Tenofovir Disoproxil Fumarate
- Levobetaxolol
- Levobunolol
- Linagliptin; Metformin
- Lisdexamfetamine
- Loop diuretics
- Loxapine
- Lurasidone
- Maprotiline
- Metformin
- Metformin; Pioglitazone
- Metformin; Repaglinide
- Metformin; Rosiglitazone
- Metformin; Saxagliptin
- Metformin; Sitagliptin
- Methamphetamine
- Methylphenidate
- Metoprolol
- Midodrine
- Molindone
- Monoamine oxidase inhibitors
- Nadolol
- Nebivolol
- Nebivolol; Valsartan
- Nonsteroidal antiinflammatory drugs
- Norepinephrine
- Nortriptyline
- Olanzapine
- Oxaliplatin
- Pamidronate
- Pemoline
- Penbutolol
- Perphenazine; Amitriptyline
- Phendimetrazine
- Phenothiazines
- Phentermine
- Phentermine; Topiramate
- Phenylephrine
- Phenylephrine; Promethazine
- Pimozide
- Pindolol
- Polymyxins
- Propranolol
- Protriptyline
- Quetiapine
- Risperidone
- Sodium Iodide
- Sodium Oxybate
- Sotalol
- Telbivudine
- Tenofovir Alafenamide
- Tenofovir Alafenamide
- Tenofovir, PMPA
- Thiothixene
- Thyroid hormones
- Timolol
- Torsemide
- Tramadol
- Tricyclic antidepressants
- Trimipramine
- Valacyclovir
- Ziprasidone
- Zoledronic Acid
