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Iopamidol Brand Names
Isovue | Isovue-M 200 | Isovue-M 300
What is Iopamidol
Iopamidol is an iodinated nonionic, low-osmolar contrast medium used for visualization during angiography and excretory urography.
In addition, an intrathecal formulation is available for use during myelography and to enhance myelographic computed tomography imaging (cisternography and ventriculography).
Iopamidol is used to enhance computed tomography head and body imaging and to investigate the presence of cerebral infarctions, active infections, arteriovenous malformations, aneurysms and lesions or tumors (both malignant and nonneoplastic) in the liver, kidneys, pancreas, aorta, abdominal cavity, pelvis, retroperitoneal space, and the mediastinum.
Iopamidol was approved by the FDA on December 31, 1985.
Indications
- angiography
- computed tomography (CT) imaging
- myelography
- urography
Side Effects
- acute generalized exanthematous pustulosis (AGEP)
- agitation
- amnesia
- anaphylactic shock
- anaphylactoid reactions
- angina
- angioedema
- anorexia
- anuria
- anxiety
- aphasia
- apnea
- arachnoiditis
- aseptic meningitis
- asterixis
- ataxia
- back pain
- bleeding
- bradycardia
- bronchospasm
- cardiac arrest
- chest pain (unspecified)
- chills
- coma
- confusion
- conjunctivitis
- cough
- cyanosis
- depression
- diaphoresis
- diarrhea
- disseminated intravascular coagulation (DIC)
- dizziness
- Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
- dysgeusia
- dyspepsia
- dyspnea
- ecchymosis
- erythema
- fatigue
- fever
- flushing
- Guillain-Barre syndrome
- hallucinations
- headache
- hematoma
- hematuria
- hot flashes
- hyperesthesia
- hyperhidrosis
- hypertension
- hypertensive crisis
- hyperthermia
- hyperthyroidism
- hypertonia
- hypotension
- hypothyroidism
- hypoxia
- injection site reaction
- involuntary movements
- irritability
- laryngeal edema
- laryngospasm
- maculopapular rash
- malaise
- meningitis
- muscle cramps
- musculoskeletal pain
- myelitis
- myocardial infarction
- myoclonia
- nasal congestion
- nausea
- neutropenia
- oliguria
- pallor
- paresis
- paresthesias
- peripheral edema
- peripheral neuropathy
- peripheral vasodilation
- petechiae
- polyuria
- pruritus
- pulmonary edema
- rash
- renal failure (unspecified)
- renal tubular necrosis
- restlessness
- retroperitoneal bleeding
- rhabdomyolysis
- rhinitis
- seizures
- sinus tachycardia
- skin discoloration
- skin necrosis
- sneezing
- Stevens-Johnson syndrome
- stroke
- syncope
- thromboembolism
- thrombosis
- thyrotoxicosis
- tissue necrosis
- toxic epidermal necrolysis
- tremor
- urinary retention
- urticaria
- ventricular fibrillation
- vertigo
- visual impairment
- vomiting
- weakness
- wheezing
- xerostomia
Monitoring Parameters
- serum creatinine/BUN
Contraindications
- alcoholism
- arteriosclerosis
- asthma
- atopy
- breast-feeding
- cardiac disease
- children
- coagulopathy
- corticosteroid therapy
- dehydration
- diabetes mellitus
- emphysema
- extravasation
- females
- geriatric
- heart failure
- hepatic disease
- hyperthyroidism
- hypothyroidism
- increased intracranial pressure
- infants
- infection
- intracranial mass
- intrathecal administration
- iodine hypersensitivity
- multiple myeloma
- multiple sclerosis
- myasthenia gravis
- neonates
- pheochromocytoma
- pregnancy
- premature neonates
- pulmonary disease
- pulmonary hypertension
- QT prolongation
- radiopaque contrast media hypersensitivity
- renal disease
- renal failure
- renal impairment
- seizure disorder
- seizures
- serious rash
- sickle cell disease
- thromboembolic disease
- thyroid disease
- thyrotoxicosis
- valvular heart disease
Interactions
- Acebutolol
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Tramadol
- Acyclovir
- Aldesleukin, IL-2
- Alogliptin; Metformin
- Aminoglycosides
- Amiodarone
- Amitriptyline
- Amitriptyline; Chlordiazepoxide
- Amoxapine
- Amphetamine
- Amphetamine; Dextroamphetamine
- Amphetamine; Dextroamphetamine Salts
- Amphotericin B
- Angiotensin-converting enzyme inhibitors
- Aprotinin
- Aripiprazole
- Asenapine
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Atenolol
- Atenolol; Chlorthalidone
- Bendroflumethiazide; Nadolol
- Benzphetamine
- Beta-blockers
- Betamethasone
- Betaxolol
- Bictegravir; Emtricitabine; Tenofovir Alafenamide
- Bisoprolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Brexpiprazole
- Brimonidine; Timolol
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Dextromethorphan; Phenylephrine
- Bumetanide
- Bupropion
- Bupropion; Naltrexone
- Caffeine
- Caffeine; Ergotamine
- Canagliflozin; Metformin
- Capreomycin
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Phenylephrine
- Carteolol
- Carvedilol
- Chlophedianol; Guaifenesin; Phenylephrine
- Chlorpheniramine; Dextromethorphan; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Phenylephrine
- Cisplatin
- Clomipramine
- Clonazepam
- Clozapine
- Cocaine
- Codeine; Phenylephrine; Promethazine
- Colistimethate, Colistin, Polymyxin E
- Cyclobenzaprine
- Cyclosporine
- Dapagliflozin; Metformin
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Deferasirox
- Desipramine
- Dexamethasone
- Dexmethylphenidate
- Dextroamphetamine
- Dextromethorphan; Diphenhydramine; Phenylephrine
- Dextromethorphan; Guaifenesin; Phenylephrine
- Diethylpropion
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Phenylephrine
- Dopamine
- Doravirine; Lamivudine; Tenofovir disoproxil fumarate
- Dorzolamide; Timolol
- Doxepin
- Efavirenz; Emtricitabine; Tenofovir
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Empagliflozin; Linagliptin; Metformin
- Empagliflozin; Metformin
- Emtricitabine; Rilpivirine; Tenofovir alafenamide
- Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
- Emtricitabine; Tenofovir alafenamide
- Emtricitabine; Tenofovir disoproxil fumarate
- Entecavir
- Ephedrine
- Ertugliflozin; Metformin
- Esmolol
- Ethacrynic Acid
- Ethanol
- Fluoxetine; Olanzapine
- Furosemide
- Glipizide; Metformin
- Glyburide; Metformin
- Green Tea
- Guaifenesin; Phenylephrine
- Haloperidol
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrocodone; Phenylephrine
- Hydrocortisone
- Ibandronate
- Iloperidone
- Imipramine
- Labetalol
- Lamivudine; Tenofovir Disoproxil Fumarate
- Levobetaxolol
- Levobunolol
- Linagliptin; Metformin
- Lisdexamfetamine
- Loop diuretics
- Lorazepam
- Loxapine
- Lurasidone
- Maprotiline
- Metformin
- Metformin; Pioglitazone
- Metformin; Repaglinide
- Metformin; Rosiglitazone
- Metformin; Saxagliptin
- Metformin; Sitagliptin
- Methamphetamine
- Methylphenidate
- Methylprednisolone
- Metoprolol
- Midodrine
- Molindone
- Monoamine oxidase inhibitors
- Nadolol
- Nebivolol
- Nebivolol; Valsartan
- Nonsteroidal antiinflammatory drugs
- Norepinephrine
- Nortriptyline
- Olanzapine
- Oxaliplatin
- Pamidronate
- Pemoline
- Penbutolol
- Perphenazine; Amitriptyline
- Phendimetrazine
- Phenothiazines
- Phentermine
- Phentermine; Topiramate
- Phenylephrine
- Phenylephrine; Promethazine
- Pimozide
- Pindolol
- Polymyxins
- Prednisolone
- Propranolol
- Protriptyline
- Quetiapine
- Risperidone
- Sodium Iodide
- Sodium Oxybate
- Sotalol
- Telbivudine
- Tenofovir Alafenamide
- Tenofovir Alafenamide
- Tenofovir, PMPA
- Theophylline, Aminophylline
- Thiothixene
- Thyroid hormones
- Timolol
- Torsemide
- Tramadol
- Tricyclic antidepressants
- Trimipramine
- Valacyclovir
- Ziprasidone
- Zoledronic Acid