Gentamicin Prednisolone Brand Name– Pred G
What is Gentamicin Prednisolone
Gentamicin prednisolone is an ophthalmic preparation that combines an aminoglycoside antibiotic with a corticosteroid.
The combination is used to treat corticosteroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial infection exists.
The gentamicin prednisolone ophthalmic suspension was approved by the FDA in June, 1988 and ophthalmic ointment was approved in December of 1989.
Indications
- bacterial conjunctivitis
- corneal abrasion
- Escherichia coli
- Haemophilus influenzae (beta-lactamase negative)
- Haemophilus influenzae (beta-lactamase positive)
- Klebsiella pneumoniae
- Neisseria gonorrhoeae
- ophthalmic infection
- Pseudomonas aeruginosa
- Serratia marcescens
- Staphylococcus aureus (MRSA)
- Staphylococcus aureus (MSSA)
- Streptococcus pneumoniae
- Streptococcus pyogenes (group A beta-hemolytic streptococci)
- uveitis
Side Effects
- angioedema
- blurred vision
- cataracts
- conjunctival hyperemia
- conjunctivitis
- contact dermatitis
- dysgeusia
- foreign body sensation
- impaired wound healing
- keratitis
- lacrimation
- ocular discharge
- ocular hypertension
- ocular infection
- ocular irritation
- ocular pain
- rash
- superinfection
- visual impairment
Monitoring Parameters
- ophthalmologic exam
Contraindications
- abrupt discontinuation
- aminoglycoside hypersensitivity
- breast-feeding
- cataracts
- children
- corticosteroid hypersensitivity
- corticosteroid withdrawal
- fungal infection
- glaucoma
- herpes simplex keratitis (dendritic keratitis)
- increased intraocular pressure
- infants
- intravenous administration
- keratitis
- mycobacterial infection
- neonates
- ocular surgery
- pregnancy
- varicella
- viral infection
Interactions
There are no drug interactions associated with Gentamicin; Prednisolone products.
