Fluoxymesterone Brand Name– ANDROXY | Halotestin
What is Fluoxymesterone
Fluoxymesterone a 17-alpha alkylated derivative of testosterone, is an oral androgen. Therapeutically, it is used for primary or hypogonadotropic hypogonadism and delayed puberty in males. Historically the drug has also been inoperable breast cancer in females.
Androgens are responsible for the normal growth and development of male sex organs and secondary characteristics.
Fluoxymesterone also inhibits the formation of estrogen, which may be the mechanism of action for breast cancer. Anabolic steroid derivatives of testosterone, such as fluoxymesterone, have been used illicitly.
Fluoxymesterone was approved by the FDA in 1956.
Indications
- breast cancer
- delayed puberty
- hypogonadism
NOTE: This drug has not been shown to be safe and effective for the enhancement of athletic performance. Due to the potential risk of serious adverse health effects, this drug should not be used for such purpose.
For androgen replacement therapy in male hypogonadism
Side Effects
- acne vulgaris
- alopecia
- amenorrhea
- anaphylactoid reactions
- anxiety
- bleeding
- clitoromegaly
- depression
- edema
- epiphyseal closure
- feminization
- gynecomastia
- headache
- heart failure
- hepatitis
- hirsutism
- hypercalcemia
- hypercholesterolemia
- jaundice
- libido decrease
- libido increase
- nausea
- oligomenorrhea
- oligospermia
- paresthesias
- peliosis hepatis
- polycythemia
- prostatic hypertrophy
- virilization
Monitoring Parameters
- LFTs
Contraindications
- breast cancer
- breast-feeding
- cardiac disease
- children
- diabetes mellitus
- geriatric
- hepatic disease
- hypercalcemia
- hypothyroidism
- pregnancy
- prostate cancer
- renal disease
Interactions
- Abarelix
- Acarbose
- Alogliptin
- Alogliptin; Metformin
- Alogliptin; Pioglitazone
- Alpha-glucosidase Inhibitors
- Azelastine; Fluticasone
- Beclomethasone
- Betamethasone
- Budesonide
- Budesonide; Formoterol
- Canagliflozin
- Canagliflozin; Metformin
- Ciclesonide
- Corticosteroids
- Cortisone
- Cyclosporine
- Dapagliflozin
- Dapagliflozin; Metformin
- Dapagliflozin; Saxagliptin
- Darbepoetin Alfa
- Deflazacort
- Degarelix
- Dexamethasone
- Dipeptidyl Peptidase-4 Inhibitors
- Empagliflozin
- Empagliflozin; Linagliptin
- Empagliflozin; Linagliptin; Metformin
- Empagliflozin; Metformin
- Epoetin Alfa
- Ertugliflozin
- Ertugliflozin; Metformin
- Ertugliflozin; Sitagliptin
- Fludrocortisone
- Flunisolide
- Fluticasone
- Fluticasone; Salmeterol
- Fluticasone; Umeclidinium; Vilanterol
- Fluticasone; Vilanterol
- Formoterol; Mometasone
- Glipizide; Metformin
- Glyburide; Metformin
- Goserelin
- Histrelin
- Hydrocortisone
- Incretin Mimetics
- Insulins
- Leuprolide
- Leuprolide; Norethindrone
- Linagliptin
- Linagliptin; Metformin
- Meglitinides
- Metformin
- Metformin; Pioglitazone
- Metformin; Repaglinide
- Metformin; Rosiglitazone
- Metformin; Saxagliptin
- Metformin; Sitagliptin
- Methoxy polyethylene glycol-epoetin beta
- Methylprednisolone
- Miglitol
- Mometasone
- Nafarelin
- Pramlintide
- Prednisolone
- Prednisone
- Saw Palmetto, Serenoa repens
- Saxagliptin
- SGLT2 Inhibitors
- Simvastatin; Sitagliptin
- Sitagliptin
- Sulfonylureas
- Thiazolidinediones
- Thyroid hormones
- Triamcinolone
- Triptorelin
- Warfarin
