Ferric Derisomaltose Brand Name– MONOFERRIC
What is Ferric Derisomaltose
Ferric derisomaltose is a parenteral iron replacement product indicated for the treatment of iron deficiency in adults who have an intolerance or unsatisfactory response to oral iron or who have non-hemodialysis dependent chronic kidney disease.
Ferric derisomaltose was shown to be noninferior to IV iron sucrose for change in hemoglobin from baseline to week 8 in 2 clinical trials. Like other parenteral iron products, hypersensitivity may also occur with ferric derisomaltose; serious and fatal anaphylactic reactions have been reported.
Indications
- iron-deficiency anemia
For the treatment of iron-deficiency anemia in patients who have an intolerance or unsatisfactory response to oral iron or who have non-hemodialysis dependent chronic kidney disease (NDD-CKD)
Side Effects
- abdominal pain
- anaphylactoid reactions
- anxiety
- arthralgia
- back pain
- chest pain (unspecified)
- chills
- constipation
- cough
- diarrhea
- dizziness
- dysgeusia
- dyspnea
- elevated hepatic enzymes
- erythema
- fatigue
- fever
- flushing
- headache
- hypertension
- hypophosphatemia
- hypotension
- injection site reaction
- loss of consciousness
- myalgia
- nausea
- paresthesias
- phlebitis
- pruritus
- rash
- seizures
- sinus tachycardia
- skin discoloration
- syncope
- urticaria
- vomiting
Monitoring Parameters
- ferritin
- hemoglobin/hematocrit
- serum iron
- transferrin
Contraindications
- breast-feeding
- hemochromatosis
- hemosiderosis
- pregnancy
- requires a specialized care setting
Interactions
No information is available regarding drug interactions associated with Ferric Derisomaltose
