Epinastine Brand Name– Elestat
What is Epinastine
Epinastine is a topical ophthalmic H1-antagonist and an inhibitor of mast cell histamine release.
Epinastine is indicated for the prevention of ocular pruritus associated with allergic conjunctivitis.
The ophthalmic product formulation is long-acting, allowing for twice daily administration; the eye solution has a pH of approximately 7 and an osmolality of approximately 250—310 mOsm/kg.
The FDA approved epinastine 0.05% ophthalmic solution (Elestat) on October 17, 2003.
Indications
- allergic conjunctivitis
- ocular pruritus
For the prevention of ocular pruritus associated with allergic conjunctivitis
Side Effects
- cough
- headache
- hyperemia
- infection
- lacrimation
- ocular irritation
- ocular pruritus
- pharyngitis
- rhinitis
- sinusitis
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- breast-feeding
- contact lenses
- pregnancy
Interactions
There are no drug interactions associated with Epinastine products.
