Echothiophate Brand Name– Phospholine Iodide
What is Echothiophate
Echothiophate is an ophthalmic cholinesterase-inhibitor miotic agent. It is used to decrease intraocular pressure in glaucoma, for treatment of strabismus, and as a miotic agent for diagnostic purposes.
Echothiophate is an indirect-acting agent that inhibits the cholinesterase enzyme, which potentiates the action of acetylcholine on the parasympathomimetic receptors.
This drug was approved by the FDA in 1959.
Indications
- glaucoma
- strabismus
NOTE: Gonioscopy is recommended prior to initiation of therapy with echothiophate.
Side Effects
- blurred vision
- cataracts
- diarrhea
- headache
- hyperhidrosis
- iritis
- lacrimation
- myasthenia
- myopia
- ocular hypertension
- ocular irritation
- ocular pain
- respiratory depression
- retinal detachment
- urinary incontinence
- uveitis
Monitoring Parameters
- intraocular pressure
- ophthalmologic exam
Contraindications
- acute myocardial infarction
- aphakia
- asthma
- bradycardia
- breast-feeding
- cardiac disease
- closed-angle glaucoma
- contact lenses
- corneal abrasion
- GI obstruction
- hypotension
- iritis
- ocular surgery
- Parkinson’s disease
- peptic ulcer disease
- pregnancy
- retinal detachment
- seizure disorder
- urinary tract obstruction
- uveitis
Interactions
There are no drug interactions associated with Echothiophate products.
