Dihydrotachysterol

Dihydrotachysterol Brand Names- DHT | Hytakerol

What is Dihydrotachysterol

Dihydrotachysterol is an oral vitamin D analog. Many vitamin D analogs are commercially available, but the responsiveness of various conditions differs based on the pharmacologic properties of each vitamin D analog.

Dihydrotachysterol is more expensive than ergocalciferol; however, it is preferred over ergocalciferol in patients with renal failure because of impaired synthesis of ergocalciferol to its most active form by the kidneys.

Dihydrotachysterol is indicated in hypocalcemia associated with hypoparathyroidism and chronic or idiopathic tetany.

Dihydrotachysterol was approved prior to 1982.

Indications

  1. hypocalcemia
  2. hypoparathyroidism
  3. hypophosphatemia
  4. renal osteodystrophy
  5. tetany

For the treatment of hypocalcemia associated with hypoparathyroidism

Side Effects

  1. hypercalcemia
  2. hyperphosphatemia
  3. hypervitaminosis D

Monitoring Parameters

  • serum calcium
  • serum creatinine/BUN
  • serum phosphate

Contraindications

  • arteriosclerosis
  • breast-feeding
  • cardiac disease
  • hypercalcemia
  • hyperphosphatemia
  • hypervitaminosis D
  • hypoparathyroidism
  • pregnancy
  • renal disease
  • renal failure
  • sarcoidosis

Interactions

  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Aluminum Hydroxide
  • Aluminum Hydroxide; Magnesium Carbonate
  • Aluminum Hydroxide; Magnesium Hydroxide
  • Aluminum Hydroxide; Magnesium Hydroxide; Simethicone
  • Aluminum Hydroxide; Magnesium Trisilicate
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Atenolol; Chlorthalidone
  • Azilsartan; Chlorthalidone
  • Benazepril; Hydrochlorothiazide, HCTZ
  • Bendroflumethiazide; Nadolol
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Burosumab
  • Calcifediol
  • Calcitonin
  • Calcitriol
  • Calcium
  • Calcium Acetate
  • Calcium Carbonate
  • Calcium Carbonate; Magnesium Hydroxide
  • Calcium Carbonate; Risedronate
  • Calcium Carbonate; Simethicone
  • Calcium Chloride
  • Calcium Gluconate
  • Calcium; Vitamin D
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Captopril; Hydrochlorothiazide, HCTZ
  • Chlorothiazide
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Cholestyramine
  • Chromium
  • Colestipol
  • Doxercalciferol
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Erdafitinib
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Hetastarch; Dextrose; Electrolytes
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Ibritumomab Tiuxetan
  • Magnesium
  • Magnesium Citrate
  • Magnesium Hydroxide
  • Magnesium Salts
  • Methyclothiazide
  • Metolazone
  • Mineral Oil
  • Orlistat
  • Paricalcitol
  • Phosphorated Carbohydrate Solution
  • Phosphorus
  • Potassium Phosphate
  • Potassium Phosphate; Sodium Phosphate
  • Thiazide diuretics
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