Betrixaban Brand Name– BEVYXXA
What is Betrixaban
Betrixaban is an oral factor Xa inhibitor indicated for venous thromboembolism (VTE) prophylaxis in adults hospitalized for an acute medical illness who are at risk for VTE due to moderate or severe restricted mobility or other risk factors.
Unlike some other anticoagulants, the anticoagulant effect of betrixaban cannot be monitored with standard laboratory testing and is not easily reversed.
Indications
- deep venous thrombosis (DVT) prophylaxis
- pulmonary embolism prophylaxis
For venous thromboembolism prophylaxis (i.e., deep venous thrombosis (DVT) prophylaxis, pulmonary embolism prophylaxis) in at-risk, acutely ill, hospitalized medical patients
Side Effects
- bleeding
- constipation
- diarrhea
- epistaxis
- GI bleeding
- headache
- hematuria
- hypertension
- hypokalemia
- infection
- intracranial bleeding
- nausea
- ocular hemorrhage
- QT prolongation
- spinal hematoma
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- bleeding
- breast-feeding
- coagulopathy
- epidural anesthesia
- hepatic disease
- lumbar puncture
- obstetric delivery
- pregnancy
- prosthetic heart valves
- renal disease
- renal failure
- renal impairment
- spinal anesthesia
Interactions
- Abciximab
- Acetaminophen; Aspirin, ASA; Caffeine
- Ado-Trastuzumab emtansine
- Alteplase
- Altretamine
- Amiodarone
- Amlodipine; Celecoxib
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- Amoxicillin; Clarithromycin; Omeprazole
- Anagrelide
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- Apixaban
- Argatroban
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- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
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