Alcaftadine

Alcaftadine Brand Name– LASTACAFT

What is Alcaftadine

Alcaftadine is a topical ophthalmic H₁-antagonist and an inhibitor of mast cell histamine release.

Alcaftadine is indicated for the prevention of ocular pruritus associated with allergic conjunctivitis.

The ophthalmic product formulation is long-acting, allowing for once daily administration; the eye solution has a pH of approximately 7 and an osmolality of approximately 290 mOsm/kg.

The FDA approved alcaftadine 0.25% ophthalmic solution (Lastacaft) in July 2010.

Indications

• allergic conjunctivitis
• ocular pruritus

For the prevention of ocular pruritus associated with allergic conjunctivitis

Side Effects

1. angioedema
2. blurred vision
3. drowsiness
4. headache
5. lacrimation
6. ocular discharge
7. ocular inflammation
8. ocular irritation
9. ocular pain
10. ocular pruritus
11. pharyngitis

Monitoring Parameters

• laboratory monitoring not necessary

Contraindications

• breast-feeding
• children
• contact lenses
• infants
• neonates
• pregnancy

Interactions

There are no drug interactions associated with Alcaftadine products.