Adapalene Brand Names – Differin | Differin Pump | Plixda
What is Adapalene
Adapalene is a topical retinoid-like drug for the treatment of mild to moderate acne vulgaris.
Unlike tretinoin, adapalene is a naphtholic acid derivative and causes less skin irritation.
Adapalene is more effective than tretinoin gel (0.025%) in the treatment of acne vulgaris.
Adapalene is commercially available as a cream, lotion, or gel and is reported to be cosmetically appealing to most patients, according to clinical trial data.
The drug was approved by the FDA June 3, 1996.
Indications
- acne vulgaris
Side Effects
- acne vulgaris
- atopic dermatitis
- blepharedema
- conjunctivitis
- contact dermatitis
- erythema
- erythema
- erythema
- photosensitivity
- pruritus
- rash
- skin discoloration
- skin irritation
- xerosis
- xerosis
- xerosis
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- breast-feeding
- children
- eczema
- geriatric
- pregnancy
- skin abrasion
- sunburn
- sunlight (UV) exposure
Interactions
- Aminolevulinic Acid
- Methoxsalen
- Photosensitizing agents (topical)
- Porfimer
- Salicylic Acid
- Sodium Thiosulfate; Salicylic Acid
- Verteporfin
