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Common causes of GIBOO

What are the common causes of GIBOO as determined by capsule endoscopy?  Capsule endoscopy identifies a source for GIBOO in 56% of cases: Small bowel angiodysplasia in 22% Small bowel ulcers in 10% Small bowel tumors in 7% Small bowel varices in 3% Luminal blood without identifiable lesion approximately 8% Esophageal or gastric source approximately …

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Endoscopic tests to evaluate the small bowel in patients with obscure GI bleeding

What other endoscopic tests are available to evaluate the small bowel in patients with obscure GI bleeding?  Various “long endoscope” endoscopy tests permit diagnosis and potential treatment. Push enteroscopy Push enteroscopy uses an enteroscope that is similar, but substantially longer than a standard UGI endoscope. The longer enteroscope allows intubation more distally, typically into the …

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How is small bowel capsule used for endoscopy of the small bowel in patients with GIBOO

How is small bowel capsule used for endoscopy of the small bowel in patients with GIBOO?  The most widely available and most commonly performed endoscopic test to evaluate the small bowel for GIBOO is small bowel capsule endoscopy. This capsule primarily supplies images of the small bowel, but can also supply limited images of the …

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Radiologic tests for GIBOO

What radiologic tests are available for patients with GIBOO and what is their yield? • Small bowel series: Yield is only approximately 10%. Disadvantages: misses angiodysplasia, and contrast in the gut obscures and precludes angiography. • Enteroclysis: Yield is approximately 15%. Disadvantages: misses angiodysplasia, and contrast in the gut obscures and precludes angiography. • Computed tomography enterography: Method is good for …

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Obscure GI bleeding

What is meant by obscure GI bleeding?  Obscure GI bleeding, sometimes referred to as GI bleeding of obscure origin (GIBOO) , is defined as recurrent or persistent GI bleeding without identifiable source despite EGD, colonoscopy, and a radiologic examination of the small bowel. The obscure bleeding may be acute and gross or occult and microscopic. Obscure GI bleeding constitutes approximately …

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Categorization of Gastrointestinal Bleeding Terms

What do the terms upper GI bleeding (UGIB), lower GI bleeding (LGIB), and middle GI bleeding (MGIB) mean?  Although this categorization is appealingly simplistic, sometimes clinically suspected MGIB, based on one negative EGD and one negative colonoscopy, turns out to be UGIB that was missed on an initial EGD or LGIB that was missed on an initial colonoscopy. This …

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How often is iron deficiency anemia caused by underlying chronic GI blood loss

How often is iron deficiency anemia caused by underlying chronic GI blood loss?  Approximately 60% of persons with iron deficiency will have an identifiable cause detected by EGD and colonoscopy: EGD demonstrates 36% (11% duodenal ulcer, 5% gastric ulcer, 3% anastomotic ulcer). Colonoscopy demonstrates 25% (cancer was most common cause). Diagnostic investigations should always be …

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