What are the recommendations for use of adenosine? Adenosine is the drug of choice in the acute management of supraventricular tachycardia. It is a short-acting agent (half-life of approximately 10 seconds) that slows atrioventricular node conduction. The initial dose is 0.1 mg/kg, given as a rapid intravascular push with an immediate saline flush. If the …
Are there minimum dosing requirements for any resuscitation drugs? • Atropine (usual dose, 0.02 mg/kg) has a minimum dosing requirement for effective reversal of bradycardia. It appears that at doses lower than 0.1 mg, atropine exerts an effect that might actually worsen bradycardia. Thus, if its use is considered for reversal of bradycardia in a child who …
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Which resuscitation drugs are effective when given via an ETT? The preferred routes of drug delivery for infants and children in cardiac arrest are IV and IO. However, there are four “traditional” resuscitation drugs that are effective when administered through the ETT. Those four are l idocaine, a tropine, n aloxone, and e pinephrine. The acronym LANE is an easy way to remember …
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If indomethacin fails to treat the headaches, what then? If indomethacin fails to successfully treat the headaches, reconsider the diagnosis and make sure there is no underlying cause. If upon further review the diagnosis of CPH or EPH is still likely, a range of drugs may show partial to complete relief in certain groups of …
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Which medications are commonly used in the treatment of fibromyalgia and myofascial pain syndrome? Tricyclic antidepressants are widely used drugs for these disorders. They are used because they have the potential to regularize sleep patterns, decrease pain and muscle spasm, and because of their mood-enhancing properties. However, many tricyclic antidepressants are on the Beers List …
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How to treat opioid related constipation? Strong evidence for efficacy has been established for stimulant (senna, bisacodyl) and osmotic laxatives (milk of magnesia). Opioid-induced constipation is predominantly mediated by gastrointestinal µ-opioid receptors. Selective blockade of these peripheral receptors might relieve constipation without compromising centrally mediated effects of opioid analgesia or precipitating withdrawal. Treat with peripherally …
How to treat opioid related pruritis? Pruritus is one of the most common side effects of epidural or intrathecal administration of opioids, with an incidence of approximately 60% versus about 15% to 18% for epidural local anesthetic administration or systemic opioids. Many drugs have been evaluated for the prevention and treatment of opioid-induced pruritus, which …