NSAIDs to treat arthritis in childhood Medication a Daily Dose (mg/kg/day) Salicylate <25 kg: 80–100 divided three times a day >25 kg: 2.5 g/m 2 /day divided three times a day (max 4000 mg/day) Choline magnesium trisalicylate 50–65 divided twice a day (max 4500 mg/day) Ibuprofen 30–50 divided twice a day (max 3200 mg/day) Naproxen (>2 years old) …
Recent evidence of treatment of Complex Regional Pain Syndrome rational approach to the treatment of Complex Regional Pain Syndrome (∗ denotes stronger recent evidence) • Stimulation of inhibitory neurons – Spinal cord stimulation∗ • Physical therapy (PT)∗ – Massage, counterirritants – Ultrasound – Electroacupuncture – Transcutaneous nerve stimulators • Antiinflammatory agents – Nonsteroidal antiinflammatory drugs (NSAIDs) – Ketorolac …
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When are medications useful in occupational injuries? NSAIDs can be effective in reducing initial pain and swelling in acute injuries. More prolonged use is recommended for chronic overuse conditions; however, patients should be monitored closely for side effects. Corticosteroid injections for chronic conditions are not definitive treatment but can be used to facilitate rehabilitation. Injections …
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How is De Quervains tenosynovitis treated? • Splint for the thumb and wrist called a forearm-based thumb spica splint. • Local corticosteroid injections may be considered, preferably guided by ultrasonography. • Surgical release if conservative therapy fails.
Potential side effects from medications used to treat Fibromyalgia • All SNRIs may increase risk for suicidal ideation upon initiation. • Many of the drugs (SNRIs, SSRIs, tramadol, others) can increase the chance of developing serotonin syndrome when used together or at high doses. Pregabalin and gabapentin do not increase this risk. Potential drug interactions need to be checked …
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What medications have been shown to be ineffective in patients with Fibromyalgia? Opioids, corticosteroids, NSAIDs, benzodiazepines, and nonbenzodiazepine hypnotics, guaifenesin, S-Adenosylmethionine, melatonin, magnesium, and DHEA are not effective and should be avoided.
FDA approved treatment for Fibromyalgia What medications are Food and Drug Administration (FDA)-approved for treatment of Fibromyalgia? How do you choose which one to use? Three medications are FDA-approved for treatment of FM: • Dual reuptake inhibitors (serotonin-norepinephrine reuptake inhibitors [SNRI]): increase serotonin and norepinephrine at synapses in the descending analgesia pathways. Duloxetine (Cymbalta): start 20 to 30 …