What is Tibolone Tibolone is a synthetic steroid, structurally related to norethynodrel, that has weak estrogenic, progestogenic, and androgenic activity. Tibolone is an oral medication that offers an alternative to conventional hormone replacement therapy for the treatment of menopausal symptoms and prevention of post-menopausal osteoporosis. Tibolone use does not require the use of additional progestin …
What is Tiagabine Tiagabine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures. It is a derivative of nipecotic acid, a compound found in the betel nut from southeast Asia. Tiagabine’s mechanism of action differs from other adjunctive therapies for partial seizures (e.g., gabapentin, lamotrigine, vigabatrin, topiramate) in that it inhibits the …
What is Thyrotropin Alfa Thyrotropin alfa is an injectable thyroid-stimulating hormone (TSH) indicated as an adjunctive diagnostic tool for serum thyroglobulin testing with or without radioiodine imaging in the follow-up of patients with well-differentiated thyroid cancer who have previously undergone thyroidectomy and as adjunctive therapy for radioiodine ablation of thyroid tissue remnants in patients who …
What is Thrombin Thrombin is a hemostatic agent. It is a component of the clotting cascade and is known as factor IIa. Thrombin is derived from prothrombin, an alpha-2-globulin produced by the liver. Bovine and recombinant thrombin are commercially available. Potency of the thrombin products is measured in terms of the amount of thrombin required …
What is Thiothixene Thiothixene is an antipsychotic drug that is structurally similar to trifluoperazine and shares some of the pharmacological properties of the high-potency antipsychotics. It is used in the treatment of psychotic disorders and schizophrenia. Five milligrams of thiothixene is equivalent to 100 mg of chlorpromazine, the prototype antipsychotic. Thiothixene was approved by the …
What is Thiotepa Thiotepa is an alkylating agent indicated for the treatment of superficial papillary carcinoma of the urinary bladder, ovarian cancer, breast cancer, Hodgkin lymphoma, non-Hodgkin lymphoma, and controlling intracavitary effusions secondary to diffuse or localized neoplastic diseases of various serosal cavities. Thiotepa was originally approved by the FDA in 1959. In 2017, Thiotepa …
What is Thioridazine Thioridazine is a piperidine phenothiazine that is structurally similar to mesoridazine, which is one of its metabolites. It is used to treat psychotic disorders such as schizophrenia. Thioridazine can produce a variety of cardiovascular adverse reactions, including dose-related QT prolongation and torsade de pointes (TdP). Because of the potential for cardiovascular …