What is Verteporfin Verteporfin is a porphyrin derivative present in a 1:1 ratio of regioisomers. As a photosensitizing agent, verterporfin is used as part of photodynamic therapy (PDT). Photodynamic therapy is a two-stage process requiring administration of the drug photosensitizer followed by an activating light source. With verteporfin, a nonthermal red light (689 nm wavelength …
What is Verapamil Verapamil is an oral and intravenous calcium-channel blocking (CCB) agent. It is useful for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias. Verapamil is considered a class IV antiarrhythmic agent and it is more effective than digoxin for controlling ventricular rate in patients with atrial fibrillation. Verapamil can be effective in …
What is Venlafaxine Venlafaxine is an oral serotonin norepinephrine reuptake inhibitor (SNRI) used in adults for treating major depression, generalized anxiety disorder, social anxiety disorder, and panic disorder. Venlafaxine is effective for hot flashes due to menopause or breast cancer treatment and is commonly used off-label in women as an alternative to hormonal therapy for …
What is Venetoclax Venetoclax is a B-cell lymphoma-2 (BCL-2) protein inhibitor that has demonstrated cytotoxic activity in tumor cells that overexpress BCL-2. It is indicated as a single agent or in combination with obinutuzumab or rituximab for the treatment of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). Venetoclax has demonstrated efficacy in CLL …
What is Vemurafenib Vemurafenib is a serine/threonine-protein kinase BRAF inhibitor. Vemurafenib is indicated for the treatment of melanoma in patients with V600E mutations of the BRAF gene; it is not indicated for use in patients with wild-type BRAF. Vemurafenib is also indicated for the treatment of Erdheim-Chester disease in patients with BRAF V600E mutations. Secondary …
What is Vedolizumab Vedolizumab is a monoclonal antibody that is a specific integrin receptor antagonist. It is used for the treatment of moderately to severely active ulcerative colitis and Crohn’s disease in adult patients. Treatment with vedolizumab is appropriate for patients who have failed to fully respond to tumor necrosis factor (TNF) blocker, immunomodulator, or …
What is Vecuronium Vecuronium is a parenteral, intermediate-acting, nondepolarizing, neuromuscular blocking agent indicated as an adjunct to general anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Vecuronium is approximately one-third more potent than pancuronium, with a shorter duration of action at initially equipotent doses. Vecuronium causes minimal …