Marstacimab – Description Indications & Dosage NOTE: Marstacimab is designated as an orphan drug by the FDA for this indication. Subcutaneous dosage Adults weighing 50 kg or more: 300 mg subcutaneously as a single dose, then 150 mg subcutaneously once weekly starting 1 week after the loading dose. Consider increasing the dose to 300 mg …
Olutasidenib – Description Indications & Dosage For the treatment of acute myelogenous leukemia (AML) NOTE: The FDA has designated olutasidenib as an orphan drug for the treatment of AML. for the treatment of relapsed or refractory AML with an isocitrate dehydrogenase-1 (IDH1) mutation NOTE: Evaluate patients for the presence of the IDH1 mutation in the blood …
Odevixibat – Description Indications & Dosage For the treatment of progressive familial intrahepatic cholestasis-associated pruritus NOTE: Odevixibat may not be effective in progressive familial intrahepatic cholestasis (PFIC) type 2 patients with ABCB11 variants resulting in nonfunctional or complete absence of bile salt export pump protein (BSEP-3).66816 Oral dosage (capsules) Adults: 40 mcg/kg/dose PO once daily in …
Relugolix – Description Indications & Dosage For use in radionuclide myocardial perfusion imaging for coronary artery disease diagnosis in patients unable to undergo adequate exercise stress Intravenous dosage Adults: 0.4 mg IV once.33906 Maximum Dosage Limits: •Adults 0.4 mg IV single dose. •Geriatric 0.4 mg IV single dose. •Adolescents Safety and efficacy have not been established. •Children …
Nipocalimab – Description Indications & Dosage Prior to nipocalimab initiation For the treatment of generalized myasthenia gravis in individuals who are anti-acetylcholine receptor (AChR) or anti-muscle-specific tyrosine kinase (MuKS) antibody positive NOTE: Nipocalimab is designated as an orphan drug by the FDA for this indication. Intravenous dosage Adults: 30 mg/kg IV infusion over 30 minutes as a …
Nogapendekin alfa inbakicept – Description Indications & Dosage For the treatment of bladder cancer For the treatment of Bacillus Calmette-Guerin (BCG)-unresponsive nonmuscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS), with or without papillary tumors, in combination with BCG Maximum Dosage Limits: •Adults 400 mcg intravesically. •Geriatric 400 mcg intravesically. •Adolescents Safety and efficacy have …
Nifurtimox – Description Indications Dosage General dosing information: This drug may also have activity against the following microorganisms: Trypanosoma brucei gambiense, Trypanosoma cruzi NOTE: Some organisms may not have been adequately studied during clinical trials; therefore, exclusion from this list does not necessarily negate the drug’s activity against the organism. For the treatment of American trypanosomiasis (Chagas disease) …