Physiologic changes that occur during pregnancy and their possible effects on patients with rheumatic diseases

Physiologic changes that occur during pregnancy and their possible effects on patients with rheumatic diseases

Other notable changes during pregnancy include:

  • • The TH2 cytokine profile is dominant during pregnancy; this may explain why patients with SLE can flare during pregnancy while RA can improve.
  • • IgG can cross the placenta starting at 13 to 16 weeks of gestation.
  • • The risk of thrombosis increases during pregnancy due to increased hepatic protein synthesis.
    • • Can be exacerbated by the presence of antiphospholipid antibodies (aPLAs).
  • • Risk of osteoporosis increases during pregnancy and lactation as calcium is pulled from the bones; this calcium loss is reversible after pregnancy and lactation are completed.
  • • Edema of pregnancy can cause or worsen carpal tunnel syndrome.
15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856