How to distinguish among different causes of acute kidney injury in pregnancy?
Causes of acute kidney injury in Pregnancy
HUS | HELLP | Lupus Nephritis | AFLP | Cortical Necrosis | |
|---|---|---|---|---|---|
| Creatinine | or nl | or nl | or nl | ||
| Platelets | or nl | or nl | nl | ||
| Transaminases | nl | ↑ | nl | nl | |
| LDH | nl | nl | |||
| PT/PTT | nl | or nl | nl | nl | |
| Schistocytes | † | † | No | No | No |
| BP | or nl | or nl | or nl | ||
| Progression | Frequent | Rare | Variable | No | Frequent |
AFLP, Acute fatty liver of pregnancy; AKI, acute kidney injury; BP, blood pressaure; HELLP , hemolytic anemia, elevated liver enzymes and low platelets; HUS, hemolytic uremic syndrome; LDH, lactate dehydrogenase; PT, prothrombin time; PTT, partial thromboplastin time.
