Neurobehavioral features of Huntingtons disease
What are the neurobehavioral characteristics of Huntington’s disease (HD)?
Development of neuropsychiatric disturbances is a common feature of HD. Minor alterations in personality and behavior are the initial symptoms in a vast majority of cases.
A wide range of neuropsychiatric symptoms have been reported, including depression, apathy, anxiety, irritability, poor self-control, perseveration, personality changes, and in many cases even frank psychosis.
Progressive neurocognitive decline is also a hallmark of HD.
Deficits in executive functioning, short-term memory, and long-term memory (including deficits in episodic, procedural, and working memory) gradually progress to development of an NCD.
