What is the wound healing defect in Ehlers Danlos syndromes?
- Ehlers-Danlos syndromes (EDS) are a heterogeneous group of connective tissue disorders characterized by hypermobile joints, hyperextensible skin, and generalized fragility of connective tissues.
- They are associated with defects in the synthesis, cross-linking, or structure of collagen that can lead to decreased wound strength and delays in wound healing.
- Patients are prone to wound dehiscence, which forms broad, thin, shiny scars resembling cigarette paper.
