What factors help to predict the course of Multiple Sclerosis

What factors help to predict the course of Multiple Sclerosis? 

The variability of Multiple Sclerosis makes accurate prediction fallible, but a few factors may portend a good prognosis:

  • Early age of onset (first symptoms before age 40)
  • Sensory symptoms at onset (as opposed to weakness, ataxia, or other motor abnormalities) 
  • A relapsing–remitting course (vs a primary progressive symptom at onset)
  • Female gender: women do better than men.

Sources

Lublin FD, Reingold SG, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, et al.: Defining the clinical course of multiple sclerosis. The 2013 revisions. Neurology 83(3):1-9, 2014.

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