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What entities constitute the vascular dementias?
• Large vessel disease (multiple small infarcts with cortical and subcortical involvement)
• Small vessel disease
• Strategic infarcts (e.g., angular gyrus syndrome with agraphia, alexia, right/left disorientation, finger agnosia, apraxia, anomia, and verbal amnesia)
Sources
- Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Gunter JL, et al.: The evolution of primary progressive apraxia of speech. Brain 137(Pt 10):2783-2795, 2014.
- Sacktor N, Robertson K: Evolving clinical phenotypes in HIV-associated neurocognitive disorders. Curr Opin HIV AIDS 9(6):517-520, 2014.