Symptoms of acute phase of Kawasaki Disease
What other clinical symptoms or conditions may be seen in the acute phase of the illness of Kawasaki Disease?
• Musculoskeletal: arthritis or arthralgia may involve large and/or small joints (7.5%–25%). Usually short-lived. Synovial fluid WBC count can be >100,000/mm 3 .
• Cardiovascular: myocarditis, pericarditis, shock, aneurysms of medium-sized arteries (20%–25%), aortic root enlargement.
• Ocular: anterior uveitis (80%).
• Respiratory: cough (30%), hoarseness.
• Gastrointestinal: vomiting and diarrhea with abdominal pain (40%–60%), pancreatitis, hepatitis (30%–40%), gallbladder hydrops.
• Genitourinary: urethritis, sterile pyuria.
• Nervous system: extreme irritability (50%), aseptic meningitis, facial nerve palsy, sensorineural hearing loss (<1%).
• Skin: inflammation at previous BCG immunization site (characteristic).
• Others: macrophage activation syndrome (MAS).