Significance of Symptoms of Kidney Disease

Significance of Symptoms of Kidney Disease

TermMeaningSignificance
OliguriaDecreased urine output (<0.5 mL/kghour in children, <400 mL/day in adults)Volume depletion; kidney failure
AnuriaSeverely decreased urine output (<100 mL/day)Kidney failure
Absolute anuriaNo (0 mL) urine outputBlocked/kinked catheter, urinary obstruction
DysuriaPain or burning while passing urineUrinary tract infections, stones, sexually transmitted infections, interstitial cystitis
HematuriaPresence of blood in urine; Gross: visible with naked eyeMicroscopic: only seen with dipstick/urinanalysisSource of blood can be urinary tract or glomerulus
ProteinuriaPresence of protein in urine, by dipstick (trace or more) or quantitationUsually suggests intrinsic kidney disease
MicroalbuminuriaVery small amounts of albumin in urine, usually missed by urine dipstickSign of early diabetic kidney damage; in nondiabetic conditions suggests endothelial dysfunction
PolyuriaIncreased amount of urine (opposite of oliguria)Increased water intake; diabetes
NocturiaIncreased frequency of urine at nightUsually accompanies polyuria; also with chronic kidney disease (decreased urinary concentrating ability)
PollakiuriaFrequent urination in the daytimeBenign condition in children; accompanies polyuria; neurogenic bladder; drugs (e.g., tolvaptan)
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