Role of LDL apheresis in kidney disease

What is the role of LDL apheresis in persons with kidney disease?

Persons who are homozygous for familial hypercholesterolemia, or those with an LDL cholesterol ≥200 mg/dL and documented coronary heart disease, or those with an LDL cholesterol ≥300 mg/dL despite medical therapy, or people intolerant of medical therapy are often candidates for LDL apheresis.

Apheresis decreases LDL cholesterol by 50% to 75% per session and are usually performed on a weekly or biweekly basis.

The above indications and results are based on small-scale studies done in the general population without specific recommendations for persons with kidney disease.

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