Role of hyperosmolar therapy in Traumatic Brain Injury

What is the role of hyperosmolar therapy in Traumatic Brain Injury? 

Mannitol is effective for control of raised ICP at doses of 0.25 gm/kg to 1 g/kg body weight.

Restrict mannitol use prior to ICP monitoring to patients with signs of transtentorial herniation or progressive neurologic deterioration not attributable to extracranial causes.

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