Red flags of secondary Raynauds Phenomenon
Red flags that would be worrisome for the potential presence or later development of a disease associated with secondary Raynauds Phenomenon
- • Onset of digital vasospasm after the age of 40 years.
- • Male sex.
- • Asymmetric attacks.
- • Trophic changes in the digits (ulcers, pits, gangrene).
- • Ischemic signs/symptoms proximal to fingers or toes.
- • Worsening symptoms despite warm environment.
- • Abnormal NCM.
- • Sclerodactyly, rashes, or other obvious evidence of an underlying condition.
- • Serologic presence of autoantibodies, especially anticentromere antibodies or antibodies against a specific nuclear antigen (SCL-70, Th/To, RNP, Sm, SS-A, SS-B).
