Pathologically distinct presentations of GBS

Pathologically distinct presentations of GBS

What are the two main pathologically distinct presentations of Guillain Barre syndrome?

1. Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) due to an immune attack on Schwann cell membrane or myelin sheath sometimes with secondary axonal damage.

2. Acute (motor or motor-sensory) axonal neuropathy (AMAN or AMSAN) due to an immune attack against the axolemma/axoplasm. AMAN is much more common in Asia and occurs mainly in children. AMSAN may occur anywhere and affects adults preferentially. AMSAN has a much worse prognosis than AMAN, with only 20% of patients with the former ambulating at 1 year.

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856
Scroll to Top