Ocular features that may be useful for distinguishing HSV and VZV from other causes of uveitis
Uveitis caused by HSV and VZV may not be associated with other characteristic ocular, cutaneous, or systemic manifestations, making the diagnosis difficult to establish. An accurate and timely diagnosis is critical so appropriate treatment can be instituted. Suggestive findings include unilateral involvement, marked anterior chamber inflammation, elevated intraocular pressure, iris atrophy or nodules, iris transillumination, and corneal hypoesthesia. Polymerase chain reaction of the aqueous humor may be required for definitive diagnosis.
