What is a myasthenic crisis?
Myasthenic crisis is an acute exacerbation of Myasthenia gravis with severe weakness and/or bulbar and/or respiratory dysfunction.
The maintenance of adequate ventilation is paramount, and patients should be hospitalized with close monitoring of pulmonary functions, especially forced vital capacity and forced expiratory volume in 1 second, which often decline before blood gases deteriorate.
Early intubation with mechanical ventilatory support is lifesaving in a myasthenic crisis.