Myasthenic crisis

What is a myasthenic crisis? 

Myasthenic crisis is an acute exacerbation of Myasthenia gravis with severe weakness and/or bulbar and/or respiratory dysfunction.

The maintenance of adequate ventilation is paramount, and patients should be hospitalized with close monitoring of pulmonary functions, especially forced vital capacity and forced expiratory volume in 1 second, which often decline before blood gases deteriorate.

Early intubation with mechanical ventilatory support is lifesaving in a myasthenic crisis.

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