Molecular markers for prognosis in medulloblastoma
Are there any molecular markers that have shown to be useful in predicting prognosis in medulloblastoma?
Integrative genomic studies propose that medulloblastoma can be divided into four molecular subgroups (WNT, SHH, Group 3, and Group 4).
WNT tumors have the best prognosis, whereas Group 3 tumors with amplification of the MYC proto-oncogene have the worst prognosis.