Metabolic myopathy
What features are suggestive of a metabolic myopathy?
Clinical features suggestive of a metabolic myopathy include acute, recurrent, and usually reversible exercise-related muscular pain, stiffness, or cramps and myoglobinuria.
Some disorders are associated with fixed or progressive weakness.
The metabolic myopathies can be further classified by the metabolic pathway that is disrupted (glycolytic metabolism, lipid metabolism, or oxidative phosphorylation, which takes place in the mitochondrial matrix).
