McAdam and Michet diagnostic criteria for Relapsing Polychondritis
- 1)McAdam LP. Medicine (Baltimore). May 1976;55(3):193–215.
- 2)Damiani JM. Laryngoscope. June 1979;89(6):929–946.
- 3)Michet CJ. Ann Intern Med. Jan 1986;104(1):74–78.
| Criteria for the Diagnosis of RPC | |
|---|---|
| (Revised) McAdam et al. 1,2 | Michet et al. 3 |
| Bilateral auricular chondritisNonerosive seronegative inflammatory polyarthritisNasal chondritisOcular inflammationRespiratory tract chondritis | Major Criteria:- Proven inflammatory episodes involving auricular cartilage- Proven inflammatory episodes involving nasal cartilage- Proven inflammatory episodes involving laryngotracheal cartilage |
| Audiovestibular damageThe presence of 3 of 6 criteria is diagnostic of RPC. One criteria + histologic confirmation is diagnostic. Two criteria + response to steroids or dapsone is diagnostic. | Minor Criteria:- Ocular inflammation (conjunctivitis, keratitis, episcleritis, uveitis)- Hearing loss- Vestibular dysfunction- Seronegative inflammatory arthritisThe presence of 2 major or 1 major + 2 minor criteria is diagnostic. |
