Mandatory Lab data before kidney biopsy

Mandatory Lab data before kidney biopsy

What laboratory data should be obtained before undertaking a kidney biopsy?

Routine laboratory tests that are obtained before biopsy include a complete biochemical profile, complete blood count, platelet count, prothrombin time, partial thromboplastin time, blood type, antibody screen for cross-matching, and a urinalysis.

The practice of obtaining bleeding times prior to a percutaneous kidney biopsy is debated among different medical centers due to the lack of randomized, prospective studies, availability, and consistency.

In a large prospective study of more than 1000 percutaneous kidney biopsies using real-time ultrasound guidance, patients with a bleeding time greater than 7.5 minutes had higher rates of biopsy-related complications.

About 50% of these patients had a serum creatinine greater than 1.5 mg/dL. However, other studies have reported no increased risk.

The use of bleeding times prior to a percutaneous kidney biopsy thus remains center dependent.

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