Juvenile myoclonic epilepsy

Juvenile myoclonic epilepsy

This syndrome is characterized by multiple seizure types including

(1) myoclonic seizures that often occur shortly after wakening,

(2) generalized tonic–clonic seizures that tend to be precipitated by sleep deprivation,

(3) absence seizures.

Interictally, the EEG typically shows a 4- to 6-Hz generalized spike-wave pattern. The generalized myoclonic jerks are associated with a generalized spike-wave discharge, and usually consciousness is not lost.

Unlike the other common idiopathic epilepsies, juvenile myoclonic epilepsy does not usually remit with age.

Valproate, topiramate, lamotrigine, levetiracetam, and primidone have been successful in treating seizures.

Some of the other newer AEDs also may prove to be beneficial.

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