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Interesting facts of HBV and HCV related glomerulopathies
The below table summarizes the key aspects of these two lesions.
Key Aspects of Hepatitis B and Hepatitis C –Related Glomerulopathies
Hepatitis C | Hepatitis B | |
|---|---|---|
| Primary glomerular disease | Type I membranoproliferative glomerulonephritis | Membranous nephropathy |
| Pathophysiology | Type II cryoglobulinemia | Hepatitis B e Ag-antibody immune complexes |
| Clinical findings | Nephritic syndrome | Nephrotic syndrome |
| Systemic manifestations | Vasculitis | None |
| Laboratory features | Low C3, C4 Positive rheumatoid factor | Normal complement levels |
| Treatment | Direct acting antivirals | Entecavir |
| Malignancy potential | Hepatoma B-cell lymphoma | Hepatoma |
