How is amyloidosis diagnosed
What is the diagnostic test for amyloidosis?
Although the diagnosis is suggested by the finding of heavy albuminuria and bland urine sediment, a tissue biopsy is required to diagnose amyloidosis and distinguish between the various types (AL, AA, and AH).
Amyloid deposits can also be found in virtually all other organs including the rectum, abdominal fat pad, and the bone marrow, and these are sometimes biopsied in preference to the kidney.
The combination of SPE and serum FLC will be abnormal in 98% of patients with primary amyloidosis as a result of an LC disorder because of the increase in the abnormal (usually λ) sFLC.
