How is Acute Kidney Injury treated?
The treatment of Acute Kidney Injury depends on the specific cause. Prerenal states need to be treated with the correction of intravascular volume depletion and the optimization of cardiac function.
Acute Kidney Injury from urinary tract obstruction needs to be treated with decompression of the urinary tract.
Acute Interstitial Nephritis is treated with discontinuation of the offending agent; however, the role of glucocorticoids therapy remains controversial.
Acute glomerular syndromes need to be treated based on the specific etiology. Abdominal compartment syndrome is treated with abdominal decompression to reduce intra-abdominal pressure.
Depending on the clinical setting, this may be accomplished with nasogastric drainage or paracentesis, but it may require surgical laparotomy, often leaving the abdomen open until edema and inflammation resolve.
The management of Acute Tubular Necrosis is entirely supportive. There are no effective pharmacologic agents.
Renal replacement therapy is used to support patients while anticipating the recovery of kidney function.