How are Erythropoiesis Stimulating Agents administered?
Human recombinant erythropoietin (epoetin) is a polypeptide hormone that, like insulin, must be given through a subcutaneous or IV route.
Subcutaneously administered epoetin, because of its slower absorption and longer half-life, is more effective than a comparable dose administered through IV.
Epoetin dose can be reduced 20% to 30% by switching patients from IV to subcutaneous dosing while achieving the same Hb.
