Histopathologic findings of Acute tubulointerstitial nephritis
- • Presence of an inflammatory cell infiltrate in the interstitium
- • Interstitial edema
- • Tubulitis
- • Other findings may include:
- • Granulomas in the interstitium. As seen in sarcoidosis, Sjögrens, and tubulointerstitial nephritis and uveitis (TINU)
- • Anti-TBM antibodies
- • Diffuse foot process effacement. As seen in NSAID-induced minimal change disease.
- • Normal glomeruli and vessels. This, in particular, distinguishes tubulointerstitial nephritis from inflammatory glomerular diseases (e.g., glomerulonephritides)