Haptoglobin Test

Haptoglobin Test – Why am I having this test?

Haptoglobin test may be used to help determine the reason for a reduced number of red blood cells (RBCs) in your blood, which is called anemia. Haptoglobin levels are low when a lot of RBCs are being destroyed in the bloodstream. RBCs may be destroyed because of:

  • Autoimmune diseases.
  • Sickle cell disease.
  • Certain medicines.
  • Some kidney diseases.

Haptoglobin may also be low in certain liver diseases.

A high haptoglobin level can occur if you have an inflammatory condition, such as ulcerative colitis or vascular diseases.

What is being tested?

This test measures the levels of haptoglobin in your blood. Haptoglobin is a protein that is made by the liver.

What kind of sample is taken?

A blood sample is required for this test. It is usually collected by inserting a needle into a blood vessel.

Tell a health care provider about:

  • All medicines you are taking, including vitamins, herbs, eye drops, creams, and over-the-counter medicines.
  • Any medical conditions you have.
  • Whether you are pregnant or may be pregnant.

How are the results reported?

Your test results will be reported as values. Your health care provider will compare your results to normal ranges that were established after testing a large group of people (reference ranges). Reference ranges may vary among labs and hospitals. For this test, common reference ranges are:

  • Adult: 50–220 mg/dL or 0.5–2.2 g/L (SI units).
  • Newborn: 0–10 mg/dL or 0–0.1 g/L (SI units).

What do the results mean?

Test results below normal values may be caused by:

  • Hemolytic anemia. This is a type of anemia that occurs when RBCs are broken down too quickly.
  • Reaction to a blood transfusion.
  • Artificial heart valve.
  • Liver disease.
  • Hematoma. This is a large, mass-like bruise under the skin.

Test results above the normal values may indicate:

  • Inflammatory diseases.
  • Infection.
  • Tissue damage.
  • Disorders of the kidney, liver, or intestines.

Talk with your health care provider about what your results mean.

Questions to ask your health care provider

Ask your health care provider, or the department that is doing the test:

  • When will my results be ready?
  • How will I get my results?
  • What are my treatment options?
  • What other tests do I need?
  • What are my next steps?

Summary

  • The haptoglobin test may be used to help determine the reason for a reduced number of red blood cells (RBCs) in your blood.
  • Haptoglobin levels are low when a lot of RBCs are being destroyed in the bloodstream, and measuring this level can help diagnose certain types of anemia. Haptoglobin may also be low in certain liver diseases.
  • Talk with your health care provider about what your results mean.
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