Are there any CT or MRI features that may indicate the presence of autoimmune pancreatitis?
Diffuse pancreatic enlargement with a sausage-like appearance is typically seen in autoimmune pancreatitis. A characteristic peripancreatic fibroinflammatory soft tissue rim may also be present, which has low attenuation, low signal intensity, and delayed phase enhancement relative to pancreatic parenchyma. Presence of extrapancreatic disease, such as sclerosing cholangitis, renal lesions, pulmonary nodules or opacities, sclerosing mesenteritis, retroperitoneal fibrosis, orbital pseudotumor, and salivary and lacrimal gland enlargement, may also suggest the diagnosis. Corticosteroids are the mainstay for initial treatment, with high rates of remission. Immunomodulatory drugs are administered as needed in patients with relapse or corticosteroid-resistant disease.