Contraindications to percutaneous kidney biopsy

What are the contraindications to percutaneous kidney biopsy?

The absolute contraindications for performing a percutaneous kidney biopsy, as defined by the Health and Public Policy Committee of the American College of Physicians in 1988, include:

• Uncooperative patient

• Solitary native kidney

• Uncontrolled severe hypertension

• Uncontrolled bleeding diathesis

With the exception of an uncontrolled bleeding diathesis, many consider these to be relative contraindications, which may be overridden in specific clinical circumstances. Percutaneous kidney biopsy of a solitary kidney has been performed successfully in small studies with technological advances of real-time ultrasound guidance and the use of automated needles. Other relative contraindications include:

• Active pyelonephritis

• Perinephric abscess

• Skin infection over the biopsy site

• Hydronephrosis

• Multiple cysts

• Kidney tumor

• Small hyperechoic kidneys

• Uncontrolled hypertension

• Hypotension

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